Somatic RAD54L: very rare; biological HRR rationale only. ESCAT IV / OncoKB Level 4.
Deterministic view of the source YAML entity. Clinical authority remains with the cited source IDs and reviewer sign-off state.
| ID | BMA-RAD54L-SOMATIC-OVARIAN |
|---|---|
| Type | Actionability |
| Status | reviewed 2026-04-27 | pending_clinical_signoff | actionability review required |
| Diseases | DIS-OVARIAN |
| Sources | SRC-CIVIC SRC-NCCN-OVARIAN-2025 |
Actionability Facts
| Biomarker | BIO-HRR-PANEL |
|---|---|
| Variant | RAD54L somatic loss-of-function |
| Disease | DIS-OVARIAN |
| ESCAT tier | IV |
| Recommended combinations | standard therapy |
| Evidence summary | Somatic RAD54L: very rare; biological HRR rationale only. ESCAT IV / OncoKB Level 4. |
Notes
Reflex germline testing optional given uncertain pathogenicity.
Used By
No reverse references found in the YAML corpus.