OpenOnco
UA EN

Onco Wiki / Actionability

NRAS in MDS — typically signals progression risk to AML. No targeted therapy in MDS-LR; H...

Deterministic view of the source YAML entity. Clinical authority remains with the cited source IDs and reviewer sign-off state.

IDBMA-NRAS-Q61R-MDS-LR
TypeActionability
Statusreviewed 2026-04-27 | pending_clinical_signoff | actionability review required
DiseasesDIS-MDS-LR
SourcesSRC-CIVIC SRC-ESMO-MDS-2021

Actionability Facts

BiomarkerBIO-RAS-MUTATION
VariantNRAS Q61R
DiseaseDIS-MDS-LR
ESCAT tierIIIB
Evidence summaryNRAS in MDS — typically signals progression risk to AML. No targeted therapy in MDS-LR; HMA still standard.

Notes

ESCAT IIIB. Under BIO-RAS-MUTATION (no dedicated BIO-NRAS-Q61R yet — flag for BIO authoring).

Used By

No reverse references found in the YAML corpus.