IDH2 R172K in MDS — same enasidenib rationale as R140Q.
Deterministic view of the source YAML entity. Clinical authority remains with the cited source IDs and reviewer sign-off state.
| ID | BMA-IDH2-R172K-MDS-HR |
|---|---|
| Type | Actionability |
| Status | reviewed 2026-04-27 | pending_clinical_signoff | actionability review required |
| Diseases | DIS-MDS-HR |
| Sources | SRC-CIVIC SRC-ESMO-MDS-2021 |
Actionability Facts
| Biomarker | BIO-IDH-MUTATION |
|---|---|
| Variant | IDH2 R172K |
| Disease | DIS-MDS-HR |
| ESCAT tier | IIA |
| Recommended combinations | enasidenib (off-label MDS) |
| Evidence summary | IDH2 R172K in MDS — same enasidenib rationale as R140Q. |
Notes
ESCAT IIA. Off-label in MDS.
Used By
No reverse references found in the YAML corpus.