Onco Wiki / drapeau rouge

Tout parent du premier degré (parent, frère, enfant biologique) ayant des antécédents...

Vue déterministe de l'entité source de la LJAM. L'autorité clinique demeure avec les ID de la source cités et l'état d'approbation de l ́examinateur.

IDRF-UNIVERSAL-FIRST-DEGREE-CANCER-FAMILY-ANY
TypeSignal d’alerte
Étatreviewed 2026-05-18 | pending_clinical_signoff
MaladiesAucune déclaration
SourcesSRC-NCCN-GENETIC-FAMILIAL-BREAST-OVARIAN-2025 SRC-NCCN-GENETIC-FAMILIAL-CRC-2025 SRC-WCRF-AICR-CUP-2018

Origine du drapeau rouge

DéfinitionAny first-degree relative (parent, full sibling, biological child) with a history of any cancer (any site, any age at diagnosis). Broad pre-triage flag intended to fire BEFORE the disease- or syndrome-specific genetic RedFlags (BRCA / Lynch / Cowden / Li-Fraumeni / FAP / VHL etc.). Captures the cohort of patients whose family pedigree has not yet been systematically evaluated. Universal RedFlag (relevant_diseases ["*"]) — does not by itself anchor to a specific cancer; serves as a routing signal to general genetic-counseling referral and family-history-aware modification of age-and-modality screening cadence. Most patients with a single first-degree relative cancer do NOT carry a high-penetrance pathogenic variant — the value of this flag is in surfacing the cohort to a structured pedigree review (Tyrer-Cuzick / BOADICEA / PREMM5 / MMRpro depending on family profile) which then either t...
Direction cliniqueenquêter
Catégorieautres

Logique de déclenchement

{
  "any_of": [
    {
      "finding": "family_first_degree_cancer_any",
      "value": true
    }
  ],
  "type": "composite_score"
}

Notes

Pre-triage universal RedFlag — fires upstream of disease-specific genetic RFs (BRCA / Lynch / Cowden / Li-Fraumeni / FAP / VHL etc.). Authoring intent: route to structured pedigree review + general genetic-counseling referral, NOT to a specific cancer-syndrome workup until a downstream disease-specific RF fires. With relevant_diseases=["*"], the engine currently does NOT attach Indication tracks via the prevention path (engine excludes "*" from disease-anchor matching at plan.py:297) — universal Indications anchored to DIS-BREAST and DIS-CRC are authored as documentation / sidecar candidates pending future engine extension (KSS §20 v0.2-C scope). STUB pending two-Clinical-Co-Lead signoff per CHARTER §6.1 dev-mode.

Utilisé par

Indication