Onco Wiki / Bandera roja

Cualquier pariente de primer grado (padre, hermano completo, hijo biológico) con una historia de cualquier...

Vista determinista de la entidad fuente YAML. La autoridad clínica sigue con los ID de fuente citados y estado de firma del revisor.

IDRF-UNIVERSAL-FIRST-DEGREE-CANCER-FAMILY-ANY
TipoSeñal de alerta
Situaciónreviewed 2026-05-18 | pending_clinical_signoff
EnfermedadesNinguna declarada
FuentesSRC-NCCN-GENETIC-FAMILIAL-BREAST-OVARIAN-2025 SRC-NCCN-GENETIC-FAMILIAL-CRC-2025 SRC-WCRF-AICR-CUP-2018

Origen de la bandera roja

DefiniciónAny first-degree relative (parent, full sibling, biological child) with a history of any cancer (any site, any age at diagnosis). Broad pre-triage flag intended to fire BEFORE the disease- or syndrome-specific genetic RedFlags (BRCA / Lynch / Cowden / Li-Fraumeni / FAP / VHL etc.). Captures the cohort of patients whose family pedigree has not yet been systematically evaluated. Universal RedFlag (relevant_diseases ["*"]) — does not by itself anchor to a specific cancer; serves as a routing signal to general genetic-counseling referral and family-history-aware modification of age-and-modality screening cadence. Most patients with a single first-degree relative cancer do NOT carry a high-penetrance pathogenic variant — the value of this flag is in surfacing the cohort to a structured pedigree review (Tyrer-Cuzick / BOADICEA / PREMM5 / MMRpro depending on family profile) which then either t...
Dirección clínicainvestigación
Categoríaotros

Lógica de activación

{
  "any_of": [
    {
      "finding": "family_first_degree_cancer_any",
      "value": true
    }
  ],
  "type": "composite_score"
}

Notas

Pre-triage universal RedFlag — fires upstream of disease-specific genetic RFs (BRCA / Lynch / Cowden / Li-Fraumeni / FAP / VHL etc.). Authoring intent: route to structured pedigree review + general genetic-counseling referral, NOT to a specific cancer-syndrome workup until a downstream disease-specific RF fires. With relevant_diseases=["*"], the engine currently does NOT attach Indication tracks via the prevention path (engine excludes "*" from disease-anchor matching at plan.py:297) — universal Indications anchored to DIS-BREAST and DIS-CRC are authored as documentation / sidecar candidates pending future engine extension (KSS §20 v0.2-C scope). STUB pending two-Clinical-Co-Lead signoff per CHARTER §6.1 dev-mode.

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