OpenOnco

Clinical Gap Audit

Generated 2026-08-17T08:07:07Z. This page tracks the largest remaining clinical-coverage gaps. It is a maintainer audit, not clinical guidance.

GapCurrentTargetStatus
Clinical sign-off15/2614 signoff-eligible entities reviewed (0.6%)>=85% reviewed before public guideline-grade claimsblocked_on_reviewers
Solid tumor 2L+ coverage23/67 solid diseases have a 2L+ algorithm; 26/67 have a 2L+ indicationEvery modeled solid disease has at least one advanced/relapsed-line algorithm and indication.coverage_gap
Surgery/radiation detail21 structured procedure entities; 9 structured radiation-course entities; 816 indications mention surgery/radiation in textDedicated modality entities for surgery and radiation with dose/fraction/intent/timing fields.coverage_gap
Supportive-care depth136/404 regimens have mandatory supportive care (33.7%); 43 have monitoring; 358 have dose adjustmentsEvery active regimen has supportive care, monitoring, dose-adjustment, and patient-watchpoint coverage.coverage_gap
Drug indication and off-label tracking1/862 inferred drug-disease-indication pairs have a first-class record; 1 carry a source-backed assessed statusEvery drug-use pair has explicit regulatory-label status, NCCN/ESMO category, and source provenance.coverage_gap
blocked_on_reviewers

Clinical sign-off

Current: 15/2614 signoff-eligible entities reviewed (0.6%)

Blocker: Cannot be fixed by code; requires qualified Clinical Co-Lead review.

Next: Batch the largest STUB queues by entity type and assign reviewer owners.

coverage_gap

Solid tumor 2L+ coverage

Current: 23/67 solid diseases have a 2L+ algorithm; 26/67 have a 2L+ indication

Blocker: Missing disease-by-disease 2L+ algorithm/indication authoring queue.

Next: Prioritize missing high-volume solid diseases, then rare solid diseases.

coverage_gap

Surgery/radiation detail

Current: 21 structured procedure entities; 9 structured radiation-course entities; 816 indications mention surgery/radiation in text

Blocker: The modality schemas and initial entities exist, but many indication-level references remain prose-only.

Next: Prioritize high-volume prose mentions; attach an existing or newly verified procedure/radiation-course entity to each reviewed indication phase.

coverage_gap

Supportive-care depth

Current: 136/404 regimens have mandatory supportive care (33.7%); 43 have monitoring; 358 have dose adjustments

Blocker: Supportive-care records exist, but regimen attachment is incomplete.

Next: Audit high-toxicity regimens first, then fill missing regimen attachments.

coverage_gap

Drug indication and off-label tracking

Current: 1/862 inferred drug-disease-indication pairs have a first-class record; 1 carry a source-backed assessed status

Blocker: The first-class model is present, but most regimen-derived drug-use pairs still need source-backed assessment.

Next: Backfill high-volume and high-risk pairs from current regulatory labels first; keep uncertain pairs explicitly not_assessed until verified.

Detailed JSON and Markdown are published under /audits/clinical_gap_audit.json and /audits/clinical_gap_audit.md.