Clinical Gap Audit

Generated 2026-10-18T12:09:59Z. This page tracks the largest remaining clinical-coverage gaps. It is a maintainer audit, not clinical guidance.

Gap	Current	Target	Status
Optional external clinical review	0/2620 signoff-eligible entities reviewed (0.0%)	Record actual additional reviews when available; no reviewer quota for solo-project releases.	`informational`
Solid tumor 2L+ coverage	23/67 solid diseases have a 2L+ algorithm; 26/67 have a 2L+ indication	Every modeled solid disease has at least one advanced/relapsed-line algorithm and indication.	`coverage_gap`
Surgery/radiation detail	21 structured procedure entities; 9 structured radiation-course entities; 819 indications mention surgery/radiation in text	Dedicated modality entities for surgery and radiation with dose/fraction/intent/timing fields.	`coverage_gap`
Supportive-care depth	136/407 regimens have mandatory supportive care (33.4%); 43 have monitoring; 358 have dose adjustments	Every active regimen has supportive care, monitoring, dose-adjustment, and patient-watchpoint coverage.	`coverage_gap`
Drug indication and off-label tracking	1/883 inferred drug-disease-indication pairs have a first-class record; 1 carry a source-backed assessed status	Every drug-use pair has explicit regulatory-label status, NCCN/ESMO category, and source provenance.	`coverage_gap`

informational

Optional external clinical review

Current: 0/2620 signoff-eligible entities reviewed (0.0%)

Blocker: External clinical review is optional and is not a development or publication blocker.

Next: Prioritize source traceability, automated checks and transparent limitations; record additional expert feedback separately.

coverage_gap

Solid tumor 2L+ coverage

Current: 23/67 solid diseases have a 2L+ algorithm; 26/67 have a 2L+ indication

Blocker: Missing disease-by-disease 2L+ algorithm/indication authoring queue.

Next: Prioritize missing high-volume solid diseases, then rare solid diseases.

coverage_gap

Surgery/radiation detail

Current: 21 structured procedure entities; 9 structured radiation-course entities; 819 indications mention surgery/radiation in text

Blocker: The modality schemas and initial entities exist, but many indication-level references remain prose-only.

Next: Prioritize high-volume prose mentions; attach an existing or newly verified procedure/radiation-course entity to each reviewed indication phase.

coverage_gap

Supportive-care depth

Current: 136/407 regimens have mandatory supportive care (33.4%); 43 have monitoring; 358 have dose adjustments

Blocker: Supportive-care records exist, but regimen attachment is incomplete.

Next: Audit high-toxicity regimens first, then fill missing regimen attachments.

coverage_gap

Drug indication and off-label tracking

Current: 1/883 inferred drug-disease-indication pairs have a first-class record; 1 carry a source-backed assessed status

Blocker: The first-class model is present, but most regimen-derived drug-use pairs still need source-backed assessment.

Next: Backfill high-volume and high-risk pairs from current regulatory labels first; keep uncertain pairs explicitly not_assessed until verified.

Detailed JSON and Markdown are published under /audits/clinical_gap_audit.json and /audits/clinical_gap_audit.md.